A6971958
BCH , 10mMinWater , 20448-79-7
Synonym(s):
2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid;BCH
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB239.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | >300 °C(lit.) |
| Boiling point: | 295.5±23.0 °C(Predicted) |
| Density | 1.256±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Aqueous Acid (Slightly) |
| form | Solid |
| pka | 2.58±0.20(Predicted) |
| color | White |
| Water Solubility | Soluble to 100 mM in water |
| InChI | 1S/C8H13NO2/c9-8(7(10)11)4-5-1-2-6(8)3-5/h5-6H,1-4,9H2,(H,10,11)/t5-,6+,8?/m1/s1 |
| InChIKey | MPUVBVXDFRDIPT-RSHNMJPRSA-N |
| SMILES | NC1(C[C@@H]2CC[C@H]1C2)C(O)=O |
| CAS DataBase Reference | 20448-79-7(CAS DataBase Reference) |
Description and Uses
2-Amino-2-norbornanecarboxylic Acid functions in the suppressive effect of I-type amino acid transporter 1 inhibition as therapeutic target on human esophageal squamous cell carcinoma. Also use in the design and preparation of KMH-233, selective and slowly reversible inhibitor of L-type amino acid transporter 1 (LAT1) which potentiates antiproliferative drug efficacy in cancer cells
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
