A6976558
Butenafine , 10mMinDMSO , 101828-21-1
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB559.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 200-202 °C |
| Boiling point: | 426.1±14.0 °C(Predicted) |
| Density | 1.032±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: 63 mg/mL (198.44 mM);Ethanol: 63 mg/mL (198.44 mM) |
| pka | 7.87±0.50(Predicted) |
| Water Solubility | Water: Insoluble |
| LogP | 6.770 (est) |
| CAS DataBase Reference | 101828-21-1(CAS DataBase Reference) |
Description and Uses
Butenafine (Mentax) is a synthetic benzylamine antifungal agent, related structurally and pharmacologically to terbinafine. It is thought to act by inhibiting the enzyme squalene 2,3-epoxidase, resulting in decreased ergosterol and corresponding increase in squalene, with subsequent cell membrane permeability alteration and cell death. It is active against dermatophytes, yeast, and Sporothrix.
