A6976858
4-(2-Aminoethyl)benzenesulfonylfluoridehydrochloride , 10mMinDMSO , 30827-99-7
Synonym(s):
AEBSF;4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride;4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonyl fluoride, HCl;4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonylfluoride, HCl, AEBSF, HCl InSolution;(4-(2-aminoetyl)-benzenesulfonyl fluoride hydrochloride)
CAS NO.：30827-99-7
Empirical Formula: C8H11ClFNO2S
Molecular Weight: 239.69
MDL number: MFCD00132962
EINECS: 608-547-2
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 175-177 °C |
| bulk density | 200kg/m3 |
| storage temp. | 2-8°C |
| solubility | H2O: soluble50mg/mL (stable for up to six months if stored refrigerated at a pH of less than 7. If a pH of greater than 7 is required, pH adjustment should be made just prior to use.) |
| form | Powder |
| color | White |
| PH | pH3.0～5.0 (10g/L, 25℃) |
| biological source | synthetic (organic) |
| Water Solubility | 10 g/L (20 ºC) |
| Sensitive | Moisture Sensitive |
| BRN | 7604627 |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions at pH <7 are stable for up to 6 months if stored in the refrigerator |
| InChI | InChI=1S/C8H10FNO2S.ClH/c9-13(11,12)8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H |
| InChIKey | WRDABNWSWOHGMS-UHFFFAOYSA-N |
| SMILES | S(C1C=CC(CCN)=CC=1)(=O)(=O)F.Cl |
| CAS DataBase Reference | 30827-99-7(CAS DataBase Reference) |
Description and Uses
AEBSF is a water soluble, irreversible, broad spectrum inhibitor of serine proteases, including trypsin, chymotrypsin, plasmin, thrombin, and kallikreins. AEBSF can also prevent the activation of the ROS generator, NADPH oxidase. At 10-50 μg, AEBSF can attenuate airway inflammation in a mouse model of airway allergy. AEBSF maintains stability in slightly acidic aqueous solutions and serves as a nontoxic alternative to the organophosphate inhibitors, PMSF and DFP.
Recommended concentrations for use are 0.1-1 mM.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313 |
| Hazard Codes | C,Xi |
| Risk Statements | 34-36/37/38 |
| Safety Statements | 45-36/37/39-26-36 |
| RIDADR | UN 3261 |
| WGK Germany | 3 |
| Hazard Note | Corrosive |
| HazardClass | 8 |
| PackingGroup | II |
| HS Code | 29214990 |
| Limited Quantities | 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) |
