A7032058
BenidipineHCl , 10mMinDMSO , 91599-74-5
Synonym(s):
(4R)-rel-3,5-Pyridinedicarboxylic acid;1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-;3-methyl 5-[(3R)-1-(phenylmethyl)-3-piperidinyl] ester;hydrochloride (1:1);KW-3049
CAS NO.:91599-74-5
Empirical Formula: C28H31N3O6
Molecular Weight: 505.56
MDL number: MFCD00906929
EINECS: 663-500-3
Pack Size | Price | Stock | Quantity |
1ml | RMB239.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 199-201°C |
storage temp. | Inert atmosphere,Store in freezer, under -20°C |
solubility | DMSO: ≥20mg/mL |
pka | 7.34(at 25℃) |
form | powder |
color | yellow |
InChIKey | DGVVISBYHUXFIU-UHFFFAOYSA-N |
SMILES | C(C1=C(NC(=C([C@H]1C1C=CC=C(C=1)N(=O)=O)C(=O)OC)C)C)(=O)O[C@@H]1CCCN(C1)CC1C=CC=CC=1.Cl |
CAS DataBase Reference | 91599-74-5(CAS DataBase Reference) |
Description and Uses
Benidipine hydrochloride is a new, long acting dihydropyridine calcium antagonist useful in the treatment of hypertension and angina pectoris. In experimental animals, benidipine hydrochloride dose dependently induced hypotension with a potency of 6 and 12 times more than nifedipine and nicardipine, respectively. It also exhibited a slow onset of action.
A dihydropyridine calcium channel blocker. Antihypertensive.