A7046458
Apigenin7-glucuronide , 10mMinDMSO , 29741-09-1
Synonym(s):
4′,5,7-Trihydroxyflavone 7-glucuronide;Apigenin 7-glucuronide;Apigenin 7-O-β-glucuronide;Scutellarin
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB559.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | >300℃ |
| Boiling point: | 841.8±65.0 °C(Predicted) |
| Density | 1.737 |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMSO : 65 mg/mL (145.62 mM; Need ultrasonic) |
| form | powder |
| pka | 2.73±0.70(Predicted) |
| color | Yellowish |
| InChIKey | JBFOLLJCGUCDQP-ZFORQUDYSA-N |
| SMILES | C12C=C(C(O)=CC=1C(=O)C=C(C1=CC=C(O)C=C1)O2)O[C@H]1[C@H](O)[C@H]([C@H](O)[C@@H](C(=O)O)O1)O |&1:20,21,23,24,26,r| |
Description and Uses
Apigenin 7-Glucuronide is a metabolite of Apigenin, which induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap juntion intracellular communication in liver cells.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| WGK Germany | 3 |
