2',5'-Dihydroxyacetophenone , 10mMinDMSO , 490-78-8

Synonym(s):
2′,5′-Dihydroxyacetophenone;2,5-Dihydroxyphenyl methyl ketone;2-Acetyl-1,4-dihydroxybenzene;2-Acetylhydroquinone;Acetylquinol

CAS NO.：490-78-8

Empirical Formula: C8H8O3

Molecular Weight: 152.15

MDL number: MFCD00002343

EINECS: 207-716-4

PRODUCT Properties

• Melting point: 204-206 °C(lit.)
• Boiling point: 234.6°C (rough estimate)
• Density: 1.2143 (rough estimate)
• refractive index: 1.4447 (estimate)
• storage temp.: Store below +30°C.
• solubility: dioxane: 50 mg/mL, clear
• pka: 9.86±0.18(Predicted)
• form: Crystals or Crystalline Powder
• color: Yellow to yellow-green
• Water Solubility: insoluble
• BRN: 637903
• InChIKey: WLDWSGZHNBANIO-UHFFFAOYSA-N
• LogP: 1.274 (est)
• CAS DataBase Reference: 490-78-8(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(2,5-dihydroxyphenyl)-(490-78-8)
• EPA Substance Registry System: Ethanone, 1-(2,5-dihydroxyphenyl)- (490-78-8)

Description and Uses

2',5'-Dihydroxyacetophenone is a natural phenolic compound that is found in many plants. It has been shown to have anti-inflammatory properties through its ability to inhibit the production of pro-inflammatory cytokines, such as tumor necrosis factor alpha and interleukin 1 beta.

1-(2,5-Dihydroxyphenyl)ethanone is an intermediate used in various synthetic preparations of pharmaceutical goods, 1-(2,5-Dihydroxyphenyl)ethanone was untilized in the synthesis of new flavonoid fatty acid esters with anti-adipogenic and glucose consumption enhancing activities.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: AM7700000
• Hazard Note: Irritant
• TSCA: Yes
• HS Code: 29145000