Bronopol , 10mMinDMSO , 52-51-7
Synonym(s):
2-Bromo-2-nitro-1,3-propanediol;BNPD;BNPK;Bronopol
CAS NO.：52-51-7
Empirical Formula: C3H6BrNO4
Molecular Weight: 199.99
MDL number: MFCD00007390
EINECS: 200-143-0
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 130-133 °C(lit.) |
| Boiling point: | 358.0±42.0 °C(Predicted) |
| Density | 2.0002 (rough estimate) |
| refractive index | 1.6200 (estimate) |
| Flash point: | 167°C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | H2O: soluble100mg/mL, clear, colorless to faintly yellow |
| form | Crystals or Crystalline Powder |
| pka | 12.02±0.10(Predicted) |
| color | White to yellow |
| Odor | odorless |
| Water Solubility | 25 g/100 mL (22 ºC) |
| Merck | 14,1447 |
| BRN | 1705868 |
| Stability: | Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong bases, strong reducing agents, acid chlorides and anhydrides, moisture. |
| Major Application | agriculture cleaning products cosmetics environmental food and beverages personal care |
| Cosmetics Ingredients Functions | PRESERVATIVE |
| Cosmetic Ingredient Review (CIR) | Bronopol (52-51-7) |
| InChI | 1S/C3H6BrNO4/c4-3(1-6,2-7)5(8)9/h6-7H,1-2H2 |
| InChIKey | LVDKZNITIUWNER-UHFFFAOYSA-N |
| SMILES | OCC(Br)(CO)[N+]([O-])=O |
| LogP | 1.150 (est) |
| CAS DataBase Reference | 52-51-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Bronopol(52-51-7) |
| EPA Substance Registry System | Bronopol (52-51-7) |
Description and Uses
Bronopol, a formaldehyde releaser, was reported as an allergen in dairy workers. In a recent case report, bronopol was contained in a lubricant jelly used for ultrasound examination and caused contact dermatitis in a veterinary surgeon.
First synthesized in 1897, bronopol was primarily used as an effective preservative agent and possesses a wide spectrum of antibacterial activity and inhibits the growth of fungi and yeasts. It can be used in the formulation of a wide variety of cosmetic and personal care products, especially in leave-on and rinse-off shampoos, creams, lotions, rinses and eye makeup to protect the product integrity by preventing or slowing bacterial growth.
Bronopol is used as a microbiocide/microbiostat in oil field systems, air washer systems, air conditioning/humidifying systems, cooling water systems, papermills, absorbent clays, metal working fluids, printing inks, paints, adhesives and consumer/institutional products. A formulating technical material is also registered.
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Safety
| Symbol(GHS) |    GHS05,GHS07,GHS09 |
| Signal word | Danger |
| Hazard statements | H302+H312-H315-H318-H335-H410 |
| Precautionary statements | P261-P273-P280-P301+P312-P302+P352+P312-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xn,N |
| Risk Statements | 21/22-37/38-41-50 |
| Safety Statements | 26-37/39-61-36/37/39 |
| RIDADR | UN 3241 4.1/PG 3 |
| WGK Germany | 2 |
| RTECS | TY3385000 |
| F | 4.2-8-9-21 |
| TSCA | TSCA listed |
| HazardClass | 4.1 |
| PackingGroup | III |
| HS Code | 29055999 |
| Storage Class | 4.1B - Flammable solid hazardous materials |
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1 Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
| Hazardous Substances Data | 52-51-7(Hazardous Substances Data) |
| Toxicity | LD50 in mice, rats (mg/kg): 350, 400 orally (Croshaw) |
| Limited Quantities | 5.0 Kg (11 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
