Home Categories Biochemical Engineering Blasticidin-S-HCl
A7081158

Blasticidin-S-HCl , 10mMinWater , 3513-03-9

Synonym(s):
Blasticidin S, Hydrochloride, Streptomyces griseochromogenes - CAS 589205 - Calbiochem;Blasticidin S, Hydrochloride, Streptomyces sp., Sterile-Filtered Aqueous Solution, Cell Culture-Tested - CAS 589205 - Calbiochem

CAS NO.:3513-03-9

Empirical Formula: C17H27ClN8O5

Molecular Weight: 458.9

MDL number: MFCD02091640

Pack Size Price Stock Quantity
1ml RMB559.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 224-225 °C (decomp)
storage temp.  −20°C
solubility  Soluble in Water (greater than 25 mg/ml)
form  Liquid
color  White
Water Solubility  Soluble in water. Insoluble in organic solvents.
Stability: Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month.
InChIKey YQXYQOXRCNEATG-DQUYGLIRNA-N
SMILES [C@@H]1(C=C[C@H](NC(=O)C[C@@H](N)CCN(C)C(=N)N)[C@@H](C(=O)O)O1)N1C=CC(N)=NC1=O.Cl |&1:0,3,8,17,r|

Description and Uses

Blasticidin S HCl (3513-03-9) is a peptidyl nucleoside antibiotic inhibiting protein synthesis in bacteria and eukaryotes.1?Inhibits translation by trapping deformed tRNA on the ribosome.1?The ABC-type transporter NppA1A2BCD is required for uptake of blasticidin S and other peptidyl nucleoside antibiotics in?Pseudomonas aeruginosa?PA14.2?Selection agent for bis, bsr and bsd transformed cells.3,4

Inhibits protein synthesis and induces apoptosis. Used to study protein synthesis at the level of peptide bond formation.

Safety

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H300
Precautionary statements  P264-P270-P301+P310-P405-P501
Hazard Codes  T+
Risk Statements  28
Safety Statements  28-36/37-45
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
1-10
HazardClass  6.1
HS Code  29349990

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