D-Arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide-d5 , 10mMinWater , 736992-21-5
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB559.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Density | 1.34±0.1 g/cm3(Predicted) |
| solubility | Methanol (Slightly), Water (Slightly) |
| pka | 10.10±0.25(Predicted) |
| form | Solid |
| color | White to Off-White |
| Sequence | H-d-Arg-dimethylTyr-Lys-Phe-NH2 |
| Stability: | Hygroscopic |
| InChIKey | SFVLTCAESLKEHH-WKAQUBQDSA-N |
| SMILES | C(N)(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC1=C(C)C=C(O)C=C1C)NC(=O)[C@@H](CCCNC(N)=N)N |
Description and Uses
Elamipretide, also known as MTP 131, is a mitochondria-targeted peptide antioxidant. Elamipretide decreases inflammation and protect against a variety of neurological illnesses. Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice. Elamipretide Promotes Mitophagosome Formation and Prevents Its Reduction Induced by Nutrient Excess in INS1 β-cells.
D-Arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide-d5 Trifluoroacetic Acid Salt is labelled D-Arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide (A769700) which is a mitochondrial-targeted compound that re-energizes ischemic mitochondria by interacting with cardiolipin. It is a cell-permeable antioxidant peptide.
