2'-Deoxyadenosinemonohydrate , 10mMinDMSO , 16373-93-6

Synonym(s):
9-(2-Deoxy-β-D-ribofuranosyl)adenine;Adenine deoxyriboside

CAS NO.：16373-93-6

Empirical Formula: C10H15N5O4

Molecular Weight: 269.26

MDL number: MFCD00149364

EINECS: 683-408-7

PRODUCT Properties

• Melting point: 187-189 °C
• refractive index: -25.5 ° (C=0.5, H2O)
• storage temp.: 2-8°C
• solubility: H2O: soluble50mg/mL, clear, colorless
• form: powder
• color: White to light beige
• biological source: synthetic (organic)
• Water Solubility: 0.3 g/100 mL (20 ºC)
• BRN: 5191174
• Stability: Stable, but air sensitive. Incompatible with strong oxidizing agents.
• InChI: InChI=1/C10H13N5O3.H2O/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7;/h3-7,16-17H,1-2H2,(H2,11,12,13);1H2/t5-,6+,7+;/s3
• InChIKey: WZJWHIMNXWKNTO-VWZUFWLJSA-N
• SMILES: NC1=NC=NC2N([C@H]3C[C@H](O)[C@@H](CO)O3)C=NC1=2.O |&1:7,9,11,r|
• CAS DataBase Reference: 16373-93-6(CAS DataBase Reference)

Description and Uses

2'-Deoxyadenosine monohydrate is an adenosine nucleotide, which can be synthesized by the enzyme adenosine kinase. 2'-Deoxyadenosine monohydrate is a competitive inhibitor of phosphodiesterase, which breaks down cyclic nucleotides to their corresponding monophosphate form. This leads to elevated levels of cAMP, which can cause neuronal death by apoptosis.

2'-Deoxyadenosineise is used by some cells as an energy source under energy stress conditions and to affect cAMP levels. 2'-dAdo is used in comparison studies of the functions of adenosine analogues on various biological processes.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P264b-P270-P301+P312-P330-P403-P501c
• Hazard Codes: Xn,Xi
• Risk Statements: 22-36/37/38-20/21/22
• Safety Statements: 24/25-37/39-36-26
• RIDADR: UN2811 6.1/PG 3
• WGK Germany: 3
• RTECS: AU7358600
• F: 10-23
• TSCA: Yes
• HazardClass: 6.1
• HS Code: 29349990
• Limited Quantities: 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)