(<i>R</i>)-(+)-Tetrahydrofuran-2-carboxylic Acid , ≥98.0% , 87392-05-0

CAS NO.：87392-05-0

Empirical Formula: C5H8O3

Molecular Weight: 116.12

MDL number: MFCD00211271

EINECS: 627-523-2

PRODUCT Properties

• alpha: +19.6±0.2°(neat) (D/20℃)
• Boiling point: 128-129 °C13 mm Hg(lit.)
• Density: 1.209 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.46(lit.)
• Flash point: >230 °F
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• pka: 3.60±0.20(Predicted)
• form: clear liquid
• color: Colorless to Light yellow
• optical activity: [α]23/D +4°, c = 1 in methanol
• BRN: 4658739
• InChI: InChI=1S/C5H8O3/c6-5(7)4-2-1-3-8-4/h4H,1-3H2,(H,6,7)/t4-/m1/s1
• InChIKey: UJJLJRQIPMGXEZ-SCSAIBSYSA-N
• SMILES: O1CCC[C@@H]1C(O)=O
• CAS DataBase Reference: 87392-05-0(CAS DataBase Reference)

Description and Uses

(R)-(+)-2-Tetrahydrofuroic acid is an important pharmaceutical intermediate compound used in the preparation of β-lactam antibiotics (Faropenem sodium), influenza antiviral drugs (Baloxavir Marboxil), hypertension drugs (Terazosin), and anticancer drugs.

(R)-(+)-2-Tetrahydrofuroic acid is a heterocyclic derivative and can be used as a pharmaceutical intermediate.

Safety

• Symbol(GHS): GHS05,GHS07
• Signal word: Danger
• Hazard statements: H302-H314
• Precautionary statements: P270-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338
• Hazard Codes: C,Xi
• Risk Statements: 22-34-36/37/38
• Safety Statements: 26-36/37/39-45-36
• RIDADR: UN 3265 8/PG 3
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• HS Code: 29321900