Sulfamethoxypyridazine , Analysis standard , 80-35-3

Synonym(s):
N¹-(6-Methoxy-d₃-3-pyridazinyl)sulfanilamide;N¹-(6-Methoxypyridazin-3-yl)sulfanilamide;4-Amino-N-(6-methoxy-d₃-3-pyridazinyl)benzenesulfonamide

CAS NO.：80-35-3

Empirical Formula: C11H12N4O3S

Molecular Weight: 280.3

MDL number: MFCD00057372

EINECS: 201-272-5

PRODUCT Properties

• Melting point: 182-183°
• Boiling point: 564.9±60.0 °C(Predicted)
• Density: 1.3936 (rough estimate)
• refractive index: 1.6200 (estimate)
• storage temp.: 2-8°C
• solubility: DMSO (Slightly), Methanol (Slightly)
• pka: 6.7(at 25℃)
• form: Crystalline Powder
• color: White to yellow
• Water Solubility: 579.5mg/L(25 ºC)
• Merck: 14,8919
• BRN: 277076
• Major Application: forensics and toxicology; pharmaceutical (small molecule)
• InChI: InChI=1S/C11H12N4O3S/c1-18-11-7-6-10(13-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15)
• InChIKey: VLYWMPOKSSWJAL-UHFFFAOYSA-N
• SMILES: C1(S(NC2=NN=C(OC)C=C2)(=O)=O)=CC=C(N)C=C1
• CAS DataBase Reference: 80-35-3(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridazine, sulfamethoxy-(80-35-3)

Description and Uses

Sulfamethoxypyridazine is a long-acting sulfonamide antibiotic with anti-inflammatory and antibacterial effects, mainly used for streptococcus, staphylococcus, Escherichia coli and other infections, especially for urinary tract infections.

Safety

• Symbol(GHS): GHS08
• Signal word: Danger
• Hazard statements: H317-H334
• Precautionary statements: P261-P272-P280-P284-P302+P352-P333+P313
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xi
• Risk Statements: 37/38-41
• Safety Statements: 26-39
• WGK Germany: 2
• RTECS: WP0400000
• F: 10
• HS Code: 29350090
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Resp. Sens. 1; Skin Sens. 1
• Toxicity: LD50 orally in mice: 1750 mg/kg, (Seki)