Schisandrin A , Analysis of standards,> 98% , 61281-38-7
Synonym(s):
Deoxyschisandrin;Deoxyschizandrin;Dimethylgomisin J;Schisandrin A;Schizandrin A
| Pack Size | Price | Stock | Quantity |
| 20MG | RMB143.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 116-117 °C |
| Boiling point: | 544.2±50.0 °C(Predicted) |
| Density | 1.080±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | powder |
| color | White to Off-White |
| LogP | 5.870 (est) |
Description and Uses
Schisandrin A is a lignan that has been found in Schisandra and has diverse biological activities. It binds to adiponectin receptor 2 (IC50 = 3.2 μM). Schisandrin A (10, 20, and 50 μM) reduces LPS-induced production of nitric oxide (NO), IL-6, and TNF-α and apoptosis in primary mouse microglial cells. It reverses P-glycoprotein-mediated doxorubicin resistance in MCF-7/dox cells when used at a concentration of 20 μM. Schisandrin A (4, 12, and 36 mg/kg) reverses short-term and spatial memory deficits, as well as decreases in cerebral superoxide dismutase (SOD) and glutathione peroxidase (GPX) activities induced by amyloid β (1-42) (Aβ42; ) in a mouse model of Alzheimer’s disease.
Schizandrin A is an extract from Schisandra chinesis. a dibenzocyclooctadiene lignan with antiinflammatory activity.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| RTECS | HP1595000 |
| HS Code | 29093090 |
