A7368712
SNX-2112 (PF-04928473) , ≥98% , 908112-43-6
CAS NO.：908112-43-6
Empirical Formula: C23H27F3N4O3
Molecular Weight: 464.48
MDL number: MFCD16038907
| Pack Size | Price | Stock | Quantity |
| 1MG | RMB423.20 | In Stock |
|
| 5MG | RMB1479.20 | In Stock |
|
| 10MG | RMB2028.00 | In Stock |
|
| 50MG | RMB5310.40 | In Stock |
|
| 100mg | RMB7056.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 265-266℃ |
| Boiling point: | 619.8±55.0 °C(Predicted) |
| Density | 1.47 |
| storage temp. | Store at -20°C |
| solubility | ≥23.05 mg/mL in DMSO; insoluble in H2O; ≥9.6 mg/mL in EtOH with gentle warming and ultrasonic |
| form | solid |
| pka | 15.07±0.50(Predicted) |
| color | White to off-white |
Description and Uses
SNX-2112 is a selective heat shock protein 90 (Hsp90) inhibitor which can exert a potent anticancer activity. Studies demonstates that SNX-2112 can exhibit a potent anticancer activity against B16 melanoma cells both in vitro and in vivo, by inhibiting cell proliferation and inducing cell cycle arrest and apoptosis in a mechanism dependent on the degredation of Hsp90 client proteins.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
