BD3095745
Pu-h71 , 98% , 873436-91-0
CAS NO.：873436-91-0
Empirical Formula: C18H21IN6O2S
Molecular Weight: 512.37
MDL number: MFCD28952784
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB345.60 | In Stock |
|
| 10mg | RMB588.00 | In Stock |
|
| 50mg | RMB2678.40 | In Stock |
|
| 100mg | RMB5208.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | >194oC (dec.) |
| Boiling point: | 650.6±65.0 °C(Predicted) |
| Density | 1.84 |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 10.16±0.29(Predicted) |
| form | Solid |
| color | Off-White to Pale Beige |
| InChI | InChI=1S/C18H21IN6O2S/c1-10(2)21-4-3-5-25-17-15(16(20)22-8-23-17)24-18(25)28-14-7-13-12(6-11(14)19)26-9-27-13/h6-8,10,21H,3-5,9H2,1-2H3,(H2,20,22,23) |
| InChIKey | SUPVGFZUWFMATN-UHFFFAOYSA-N |
| SMILES | N1C2C(=NC=NC=2N)N(CCCNC(C)C)C=1SC1=C(I)C=C2OCOC2=C1 |
Description and Uses
Trifluoroacetic Acid of PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM). Hsp90 plays a critical role in modulating the activity of many cell signaling proteins and are an attractive target for anti-cancer therapeutics. Studies indicate that Hsp90 inhibitors may serve as potential anti-Parkinson′s disease.
