A7571458
Go6976 , 10mMinDMSO , 136194-77-9
Synonym(s):
Gö 6976 - CAS 136194-77-9 - Calbiochem;Go 6976, 12-(2-Cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo(2,3-a)pyrrolo(3,4-c)-carbazole;Go 6976, Solution, 12-(2-Cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo(2,3-a)pyrrolo(3,4-c)-carbazole;InSolution Gö 6976 - CAS 136194-77-9 - Calbiochem
CAS NO.：136194-77-9
Empirical Formula: C24H18N4O
Molecular Weight: 378.43
MDL number: MFCD00236434
EINECS: 200-258-5
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB559.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | >221°C (dec.) |
| Boiling point: | 652.3±55.0 °C(Predicted) |
| Density | 1.41±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Acetonitrile (Very Slightly, Heated), DMSO (Slightly), Methanol (Very Slightly) |
| form | Off-white solid |
| pka | 14.39±0.20(Predicted) |
| color | White to Off-White |
| InChI | InChI=1S/C24H18N4O/c1-27-17-9-4-2-7-14(17)20-21-16(13-26-24(21)29)19-15-8-3-5-10-18(15)28(12-6-11-25)23(19)22(20)27/h2-5,7-10H,6,12-13H2,1H3,(H,26,29) |
| InChIKey | VWVYILCFSYNJHF-UHFFFAOYSA-N |
| SMILES | N1(C)C2=C(C=CC=C2)C2=C1C1N(CCC#N)C3=C(C=1C1CNC(=O)C=12)C=CC=C3 |
Description and Uses
Go 6976 is a potent FLT3 inihibtor which is been shown to initiate cytotoxicity involving acute leukemia. Also known as a PKC inhibitor, which results into apoptosis and tumor destruction. Cancer therapeutic agent.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Safety Statements | 22-24/25 |
| HS Code | 2933998090 |
