BD0994832
1H-indole-5-carboxamide , 97% , 1670-87-7
Synonym(s):
Indole-5-carboxamide;p38 MAP Kinase Inhibitor VII, SD-169 - CAS 1670-87-7 - Calbiochem
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB182.40 | In Stock |
|
| 250mg | RMB283.20 | In Stock |
|
| 1g | RMB756.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 159-163 °C |
| Boiling point: | 457.6±18.0 °C(Predicted) |
| Density | 1.328±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 16.25±0.30(Predicted) |
| form | Off-white solid |
| color | Off-White to Light Purple |
| Water Solubility | water: 1mg/mL DMSO: 10mg/mL |
| InChI | 1S/C9H8N2O/c10-9(12)7-1-2-8-6(5-7)3-4-11-8/h1-5,11H,(H2,10,12) |
| InChIKey | GQMYQEAXTITUAE-UHFFFAOYSA-N |
| SMILES | [nH]1c2c(cc1)cc(cc2)C(=O)N |
Description and Uses
1H-Indole-5-carboxamide (SD-169) is a p38α MAPK-selective inhibitor. 1H-Indole-5-carboxamide (SD-169) prevents the development and progression of diabetes in nonobese diabetic (NOD) mice by inhibiting T cell infiltration and activation.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26 |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
