A7583658
Elacridar , 10mMinDMSO , 143664-11-3
Synonym(s):
GF120918;GG918;GW0918;N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide
CAS NO.:143664-11-3
Empirical Formula: C34H33N3O5
Molecular Weight: 563.64
MDL number: MFCD00912604
EINECS: 1532714-185-1
Pack Size | Price | Stock | Quantity |
1ml | RMB538.40 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 216-218°C |
Boiling point: | 701.6±60.0 °C(Predicted) |
Density | 1.264±0.06 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | DMSO: soluble2mg/mL (clear solution, warmed) |
pka | 12.58±0.70(Predicted) |
form | powder |
color | white to beige |
InChIKey | OSFCMRGOZNQUSW-UHFFFAOYSA-N |
SMILES | C1=C2C(NC3=C(C2=O)C=CC=C3OC)=C(C(NC2=CC=C(CCN3CCC4=C(C3)C=C(OC)C(OC)=C4)C=C2)=O)C=C1 |
CAS DataBase Reference | 143664-11-3(CAS DataBase Reference) |
Description and Uses
Elacridar has been used:
- as a chemical to decipher the link between autophagy and the mechanism of resistance to sunitinib
- as an ATP-binding cassette sub-family B member 1 inhibitor to study its effects on the NSC23766 cytotoxicity
- to treat rhodamine 123 (Rh123) labeled cells to set sorting gates in fluorescence-activated cell sorting (FACS)