Ebselen , 10mMinDMSO , 60940-34-3

Synonym(s):
2-Phenyl-1,2-benzisoselenazol-3(2H)-one;Anti-Hemagglutinin-Tag antibody produced in rabbit

CAS NO.：60940-34-3

Empirical Formula: C13H9NOSe

Molecular Weight: 274.18

MDL number: MFCD00210937

EINECS: 612-054-8

PRODUCT Properties

• Melting point: 176-182 °C
• Boiling point: 402.8±28.0 °C(Predicted)
• storage temp.: 2-8°C
• solubility: Soluble in ethanol, methanol, acetone, acetonitrile.
• form: Crystalline Powder
• pka: -0.40±0.20(Predicted)
• color: Yellow to beige
• biological source: rabbit
• Merck: 14,3486
• Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
• InChI: InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H
• InChIKey: DYEFUKCXAQOFHX-UHFFFAOYSA-N
• SMILES: [Se]1C2=C(C=CC=C2)C(=O)N1C1=CC=CC=C1
• CAS DataBase Reference: 60940-34-3(CAS DataBase Reference)

Description and Uses

Ebselen is one of the selenium-containing anti-inflammatory drugs.In 2003, Rocha and co-workers identified diselenides as a new class of antiinflammatory agents.In 2014, Nogueira and co-workers reported the synthesis and anti-inflammatory activity of salicyclic-based diselenides and selenocynates.Recently, Wilhelm and co-workers identified 4-phenylselenyl-7-chloroquinoline 270 as a potent antiinflammatory compound.

antioxidant, lipoxygenase inhibitor, inhibits oxidation of LDL

Safety

• Symbol(GHS): GHS06,GHS08,GHS09
• Signal word: Danger
• Hazard statements: H301+H331-H373-H410
• Precautionary statements: P260-P264-P273-P301+P310-P304+P340+P311-P314
• Hazard Codes: T,N,Xi
• Risk Statements: 23/25-33-50/53-36/37/38
• Safety Statements: 20/21-28-45-60-61-28A-36/37-26
• RIDADR: UN 3283 6.1/PG 3
• WGK Germany: 3
• RTECS: DE4140750
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29310099