5’-EthylcarboxamidoAdenosine , 10mMinDMSO , 35920-39-9

Synonym(s):
(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxytetrahydrofuran-2-carboxamide;Adenosine Receptor Agonist, NECA - CAS 35920-39-9 - Calbiochem;NECA

CAS NO.：35920-39-9

Empirical Formula: C12H16N6O4

Molecular Weight: 308.29

MDL number: MFCD00069195

PRODUCT Properties

• Melting point: 229-231°C
• Density: 1.87±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.2 mg/mL Solutions may be stored for several days at 4°C.
• pka: 12.93±0.70(Predicted)
• form: powder
• color: white
• Water Solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.2mg/mL (Solutions may be stored for several days at 4 °C.); DMSO: 14mg/mL (Solutions may be stored for several days at 4 °C.); 0.1 M HCl: 3.4mg/mL (Solutions may be stored for several days at 4 °C.); H2O: insoluble; ethanol: soluble (Solutions may be stored for several days at 4 °C.)
• Stability: Hygroscopic
• InChI: InChI=1/C12H16N6O4/c1-2-14-11(21)8-6(19)7(20)12(22-8)18-4-17-5-9(13)15-3-16-10(5)18/h3-4,6-8,12,19-20H,2H2,1H3,(H,14,21)(H2,13,15,16)/t6-,7+,8-,12+/s3
• InChIKey: JADDQZYHOWSFJD-FLNNQWSLSA-N
• SMILES: N1(C=NC2C(N)=NC=NC1=2)[C@H]1[C@H](O)[C@H](O)[C@@H](C(=O)NCC)O1 |&1:10,11,13,15,r|
• CAS DataBase Reference: 35920-39-9

Description and Uses

5′-(N-Ethylcarboxamido)adenosine has been used:

• for the purification of human adenosine A_2Areceptor (A_2AR) in decylmaltoside (DM)
• to determine nonspecific binding of adenosine receptors
• to investigate adenosine 2B receptor (RA2B) mechanism of action by competition assay

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H300
• Precautionary statements: P264-P270-P301+P310-P405-P501
• Hazard Codes: T+
• Risk Statements: 28
• Safety Statements: 22-26-36-45
• RIDADR: UN 2811 6.1/PG 2
• WGK Germany: 3
• RTECS: VJ2232000
• HazardClass: 6.1(a)
• PackingGroup: I
• HS Code: 29349990