A7622058
ItoprideHydrochloride , 10mMinDMSO , 122892-31-3
Synonym(s):
N-[[4-[2-(Dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxy benzamidehydrochloride;N-[p-[2-(dimethylamino)ethoxy]benzyl]veratramide hydrochloride
CAS NO.：122892-31-3
Empirical Formula: C20H27ClN2O4
Molecular Weight: 394.89
MDL number: MFCD00881710
EINECS: 602-905-1
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB239.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 194-1950C |
| storage temp. | 2-8°C |
| solubility | H2O: ≥48mg/mL |
| form | powder |
| color | white to tan |
| Water Solubility | H2O: ≥48mg/mL |
| λmax | 258nm(MeOH)(lit.) |
| Merck | 14,5244 |
| InChI | InChI=1S/C20H26N2O4.ClH/c1-22(2)11-12-26-17-8-5-15(6-9-17)14-21-20(23)16-7-10-18(24-3)19(13-16)25-4;/h5-10,13H,11-12,14H2,1-4H3,(H,21,23);1H |
| InChIKey | ZTOUXLLIPWWHSR-UHFFFAOYSA-N |
| SMILES | C1(C(=O)NCC2=CC=C(OCCN(C)C)C=C2)=CC=C(OC)C(OC)=C1.Cl |
| CAS DataBase Reference | 122892-31-3(CAS DataBase Reference) |
Description and Uses
Itopride, a gastroprokinetic benzamide derivative was launched in Japan for the relief of gastrointestinal symptoms in patients with chronic gastritis. ltopride is a dopamine D2-receptor antagonist that stimulates acetylcholine (Ach) release on the postganglionic cholinergic neurons to cause Ach accumulation at muscarinic receptors and, therefore, enhances Ach-induced gastric contractions. In animal models, itopride was reported to increase GI transit and gastric emptying.
Anti-Spasmodics
