Tropinone , 99% , 532-24-1

Synonym(s):
8-Methyl-8-azabicyclo[3.2.1]octan-3-one

CAS NO.：532-24-1

Empirical Formula: C8H13NO

Molecular Weight: 139.19

MDL number: MFCD00005549

EINECS: 208-530-6

PRODUCT Properties

• Melting point: 40-44 °C(lit.)
• Boiling point: 113 °C25 mm Hg(lit.)
• Density: 1.0268 (rough estimate)
• refractive index: 1.4598 (estimate)
• Flash point: 194 °F
• storage temp.: Inert atmosphere,2-8°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: crystalline
• pka: 8.93±0.20(Predicted)
• color: brown
• PH: 8 (18g/l, H2O, 20℃)
• BRN: 2329
• InChIKey: QQXLDOJGLXJCSE-KNVOCYPGSA-N
• CAS DataBase Reference: 532-24-1(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Azabicyclo[3.2.1]octan-3-one, 8-methyl-(532-24-1)
• EPA Substance Registry System: 8-Azabicyclo[3.2.1]octan-3-one, 8-methyl- (532-24-1)

Description and Uses

Tropinone (8-methyl-8-azabicyclo[3.2.1]octane-3-one)(7) is the simplest plant tropane and is the first intermediate in the biosynthesis of tropane alkaloids.  Studies have called 4-(1-methyl-2-pyrrolidinyl)-3-oxobutanoic acid as an intermediate metabolite in tropinone biosynthesis[1]. It is an intermediate of atropine sulfate and is used in the synthesis of atropine. Atropine is an anticholinergic drug. It acts as an M-blocker and is indicated for the relief of visceral colic.

Tropinone is an oxidative product of Tropane, used to synthesize Morphine and Tropane alkaloids.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302+H332
• Precautionary statements: P261-P264-P270-P271-P301+P312-P304+P340+P312
• Hazard Codes: C,Xi
• Risk Statements: 34-22-36/37/38
• Safety Statements: 23-24/25-36/37/39-26-22
• RIDADR: 1544
• WGK Germany: 3
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29399990