4-(Trifluoromethoxy)phenylboronic acid , 98% , 139301-27-2

Synonym(s):
4-(Trifluoromethoxy)benzeneboronic acid

CAS NO.：139301-27-2

Empirical Formula: C7H6BF3O3

Molecular Weight: 205.93

MDL number: MFCD01074648

EINECS: 000-000-0

PRODUCT Properties

• Melting point: 123-127 °C(lit.)
• Boiling point: 256.6±50.0 °C(Predicted)
• Density: 1.41±0.1 g/cm3(Predicted)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: soluble in Methanol
• pka: 8.29±0.10(Predicted)
• form: Crystalline Powder
• color: White to beige
• BRN: 8548201
• InChI: InChI=1S/C7H6BF3O3/c9-7(10,11)14-6-3-1-5(2-4-6)8(12)13/h1-4,12-13H
• InChIKey: HUOFUOCSQCYFPW-UHFFFAOYSA-N
• SMILES: B(C1=CC=C(OC(F)(F)F)C=C1)(O)O
• CAS DataBase Reference: 139301-27-2(CAS DataBase Reference)

Description and Uses

B-[4-(Trifluoromethoxy)phenyl]boronic Acid is a reagent used in the synthesis of orally bioavailable matrix metalloprotinase inhibitors. Also used in the preparation of chromen-4-one inhibitors used against DNA dependant protein kinases.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a
• Hazard Codes: Xi,Xn
• Risk Statements: 36/37/38-20/21/22
• Safety Statements: 37/39-26-36
• WGK Germany: 3
• Hazard Note: Irritant
• HS Code: 29319090