A7673658
3-Indoleacetonitrile , 10mMinDMSO , 771-51-7
Synonym(s):
(3-Indolyl)acetonitrile;3-(Cyanomethyl)indole;IAN;Indolylacetonitrile;NSC 523272
CAS NO.：771-51-7
Empirical Formula: C10H8N2
Molecular Weight: 156.18
MDL number: MFCD00005628
EINECS: 212-232-1
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 33-36 °C(lit.) |
| Boiling point: | 157-160 °C0.2 mm Hg(lit.) |
| Density | 1.1566 (rough estimate) |
| refractive index | 1.6085-1.6105 |
| Flash point: | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform, DMSO (Slightly), Methanol (Slightly) |
| pka | 16.32±0.30(Predicted) |
| form | Liquid |
| color | Clear colorless to yellow |
| BRN | 125488 |
| InChIKey | DMCPFOBLJMLSNX-UHFFFAOYSA-N |
| CAS DataBase Reference | 771-51-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 1H-Indole-3-acetonitrile(771-51-7) |
| EPA Substance Registry System | 1H-Indole-3-acetonitrile (771-51-7) |
Description and Uses
Reactant for preparation of:
- Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
- Histone deacetylase inhibitors
- Potential kinase inhibitors
- Kv7/KCNQ potassium channel activators
- Kinesin-Specific MKLP-2 Inhibitor
- Pesticides
- Potential PET cancer imaging agents
- Agonists of the Farnesoid X Receptor (FXR) as atherosclerosis treatment
- Butyrylcholinesterase inhibitors
- Necroptosis inhibitors
Safety
| Symbol(GHS) |   GHS06,GHS07 |
| Signal word | Danger |
| Hazard statements | H301+H311+H331-H302-H312-H332 |
| Precautionary statements | P280h-P301+P312a-P304+P340-P321-P501a-P261-P264-P270-P271-P280-P301+P310+P330-P302+P352+P312+P361+P364-P304+P340+P311-P403+P233-P405-P501 |
| Hazard Codes | Xn,Xi |
| Risk Statements | 20/21/22 |
| Safety Statements | 36/37 |
| RIDADR | 3276 |
| WGK Germany | 3 |
| RTECS | AM0700000 |
| Hazard Note | Irritant |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29339990 |
