A7679258
Motesanib , 10mMinDMSO , 453562-69-1
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB399.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 147-150°C |
| Boiling point: | 517.3±50.0 °C(Predicted) |
| Density | 1.251 |
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | White powder solid. |
| pka | 11.75±0.40(Predicted) |
| color | Pale Yellow |
| InChI | InChI=1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28) |
| InChIKey | RAHBGWKEPAQNFF-UHFFFAOYSA-N |
| SMILES | C1(NCC2C=CN=CC=2)=NC=CC=C1C(NC1=CC2=C(C=C1)C(C)(C)CN2)=O |
Description and Uses
Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3, PDGFR, c-Kit and Ret with IC50 of 2 nM/3 nM/6 nM, 84 nM, 8 nM and 59 nM, respectively.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P362+P364-P302+P352-P305+P351+P338 |
| HS Code | 2933399990 |
