A7685612
p-Toluenesulfonyl isocyanate , 96% , 4083-64-1
Synonym(s):
p-Tosyl isocyanate;Tosyl isocyanate;TsNCO
CAS NO.：4083-64-1
Empirical Formula: C8H7NO3S
Molecular Weight: 197.21
MDL number: MFCD00002030
EINECS: 223-810-8
| Pack Size | Price | Stock | Quantity |
| 25G | RMB27.20 | In Stock |
|
| 100G | RMB62.40 | In Stock |
|
| 500G | RMB218.40 | In Stock |
|
| 2.5kg | RMB836.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 5°C |
| Boiling point: | 144 °C10 mm Hg(lit.) |
| Density | 1.291 g/mL at 25 °C(lit.) |
| vapor pressure | 1 mm Hg ( 100 °C) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | Liquid |
| color | Clear colorless to yellow |
| Specific Gravity | 1.291.291 |
| Odor | acrid odor |
| Water Solubility | reacts |
| Sensitive | Moisture Sensitive |
| BRN | 391287 |
| InChI | 1S/C8H7NO3S/c1-7-2-4-8(5-3-7)13(11,12)9-6-10/h2-5H,1H3 |
| InChIKey | VLJQDHDVZJXNQL-UHFFFAOYSA-N |
| SMILES | Cc1ccc(cc1)S(=O)(=O)N=C=O |
| LogP | 0.6 at 30℃ |
| CAS DataBase Reference | 4083-64-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Methylbenzenesulfonyl isocyanate(4083-64-1) |
| EPA Substance Registry System | Benzenesulfonyl isocyanate, 4-methyl- (4083-64-1) |
Description and Uses
It is a reagent used to prepare acetylated syn-1,2-diols,oxazolidin-2-ones, 2,3-diamino acids, and N-tosylcarbonamides. -Toluenesulfonyl isocyanate has been used as derivatization reagent in determination of 3-α-hydroxy tibolone in human plasma by LC-MS/MS. It is also employed in the derivatization reagent in simultaneous quantitative analysis of diethylene glycol and propylene glycol in pharmaceutical products by HPLC and as reagent in the preparation of acetylated syn-1,2-diols, oxazolidin-2-ones, 2,3-diamino acids and N-tosylcarbonamides.
Safety
| Symbol(GHS) |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H315-H319-H334-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| Hazard Codes | Xn |
| Risk Statements | 14-36/37/38-42 |
| Safety Statements | 26-28-30-28A |
| RIDADR | UN 2206 6.1/PG 3 |
| WGK Germany | 1 |
| RTECS | DB9032000 |
| F | 10 |
| TSCA | TSCA listed |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29309090 |
| Storage Class | 10 - Combustible liquids |
| Hazard Classifications | Eye Irrit. 2 Resp. Sens. 1 Skin Irrit. 2 STOT SE 3 |
