Titanocene dichloride , 97% , 1271-19-8
Synonym(s):
Cp2TiCl2;Titanocene dichloride;Dichlorotitanocene;Di(cyclopentadienyl)titanium(IV) dichloride;Dichlorobis(1,3-cyclopentadiene)titanium
CAS NO.：1271-19-8
Empirical Formula: C10H10Cl2Ti
Molecular Weight: 248.96
MDL number: MFCD00003723
EINECS: 215-035-9
| Pack Size | Price | Stock | Quantity |
| 5G | RMB32.80 | In Stock |
|
| 25G | RMB126.40 | In Stock |
|
| 100G | RMB409.60 | In Stock |
|
| 500g | RMB1686.40 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 260-280 °C (dec.)(lit.) |
| Boiling point: | 355.52°C (estimate) |
| Density | 1.6 g/mL at 25 °C(lit.) |
| vapor pressure | 0.002Pa at 25℃ |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | slightly soluble in H2O, benzene; soluble in chloroform,ethanol, toluene |
| form | crystal |
| Specific Gravity | 1.6 |
| color | red |
| Water Solubility | slow decomposition |
| Sensitive | Air & Moisture Sensitive |
| Hydrolytic Sensitivity | 4: no reaction with water under neutral conditions |
| Merck | 14,9482 |
| Stability: | Stable. Incompatible with strong oxidizing agents. Decomposes in water. Moisture sensitive. |
| InChI | 1S/2C5H5.2ClH.Ti/c2*1-2-4-5-3-1;;;/h2*1-5H;2*1H;/q;;;;+2/p-2 |
| InChIKey | XKLWATAZDMHTSH-UHFFFAOYSA-L |
| SMILES | Cl[Ti]Cl.[CH]1[CH][CH][CH][CH]1.[CH]2[CH][CH][CH][CH]2 |
| LogP | -1.35 at 20℃ |
| CAS DataBase Reference | 1271-19-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Titanocene dichloride(1271-19-8) |
| EPA Substance Registry System | Titanocene dichloride (1271-19-8) |
Description and Uses
Titanocene dichloride is an organotitanium compound with the chemical formula (η5-C5H5)2TiCl2, often written as Cp2TiCl2, which is a common reagent in organometallic chemistry and organic synthesis. Cp2TiCl2 does not form a "sandwich" structure like ferrocene, but a tetrahedral structure due to its four ligands around a metal center. Because of its anti-tumor activity, it has been used in clinical trials as a chemotherapeutic agent.
Titanocene dichloride is used as an experimental cancer chemotherapeutic agent. It is used as a research chemical, as a catalyst in Ziegler–Natta polymerization reactions, and as an implant material in orthopedics, oral surgery, and neurosurgery.This metallocene is a common reagent in organometallic and organic synthesis. Titanocene dichloride is used to prepare titanocene pentasulfide. Used as an anticancer drug.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi,T |
| Risk Statements | 37/38-61-40-34-33-36/37/38 |
| Safety Statements | 36-7/8-6A-45-36/37/39-26 |
| RIDADR | UN3261 |
| WGK Germany | 3 |
| RTECS | XR2050000 |
| F | 8-10-21 |
| TSCA | TSCA listed |
| HazardClass | 8 |
| PackingGroup | II |
| HS Code | 29310095 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Aquatic Acute 1 Aquatic Chronic 1 Eye Dam. 1 STOT SE 3 |
| Hazardous Substances Data | 1271-19-8(Hazardous Substances Data) |
| Toxicity | Titanocene dichloride may cause skin and mucous membrane irritation. The LD50 in mice has been reported as 60 mg/kg (i.p.) and 180 mg/kg (i.v.). In the rat, the LD50 is 25 mg/kg (i.p.). |
| REACH Registrations | Active |
