Trimethylsilyl azide , 93% , 4648-54-8

Synonym(s):
Azidotrimethylsilane;Trimethylsilyl azide

CAS NO.：4648-54-8

Empirical Formula: C3H9N3Si

Molecular Weight: 115.21

MDL number: MFCD00001986

EINECS: 225-078-5

PRODUCT Properties

• Melting point: -95°C
• Boiling point: 92-95 °C(lit.)
• Density: 0.876 g/mL at 20 °C(lit.)
• refractive index: n20/D 1.415(lit.)
• Flash point: 74 °F
• storage temp.: 2-8°C
• solubility: Miscible with toluene, dichloromethane, diethyl ether and most organic solvents.
• form: Liquid
• Specific Gravity: 0.868
• color: Clear colorless to slightly yellow
• Water Solubility: decomposes
• Sensitive: Moisture Sensitive
• Hydrolytic Sensitivity: 8: reacts rapidly with moisture, water, protic solvents
• BRN: 1903730
• InChIKey: SEDZOYHHAIAQIW-UHFFFAOYSA-N
• CAS DataBase Reference: 4648-54-8(CAS DataBase Reference)
• NIST Chemistry Reference: Azidotrimethylsilane(4648-54-8)
• EPA Substance Registry System: Azidotrimethylsilane (4648-54-8)

Description and Uses

Trimethylsilyl azide is used as an azidonation reagent for amines, amides, aldehydes and ketones. It is involved in the preparation of alfa- and beta-siloxy azides from carbonyl compounds and epoxides. It is also used in the preparation of heterocyclic compounds and also acts as an effective substitute for hydrazoic acid. Further, it is used in the Oseltamivir total synthesis.

Safety

• Symbol(GHS): GHS02,GHS06
• Signal word: Danger
• Hazard statements: H225-H301+H311+H331
• Precautionary statements: P210-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311
• Hazard Codes: F,T,N
• Risk Statements: 11-23/24/25-50/53-29
• Safety Statements: 16-36/37/39-45-8-57-36/37-29
• RIDADR: UN 1992 3/PG 2
• WGK Germany: 3
• F: 10-33
• Autoignition Temperature: 300 °C
• TSCA: Yes
• HazardClass: 3
• PackingGroup: II
• HS Code: 29310095
• Limited Quantities: 1.0 L (0.3 gallon) (liquid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)