o-Toluoyl chloride , 98% , 933-88-0

Synonym(s):
2-Methylbenzoyl chloride

CAS NO.：933-88-0

Empirical Formula: C8H7ClO

Molecular Weight: 154.59

MDL number: MFCD00000668

EINECS: 213-273-8

PRODUCT Properties

• Melting point: 159.5-160.9 °C(Solv: ligroine (8032-32-4); dichloromethane (75-09-2))
• Boiling point: 213 °C
• Density: 1.19
• refractive index: 1.55
• Flash point: 101 °C
• storage temp.: Room Temperature, Under Inert Atmosphere
• form: clear liquid
• color: Colorless to Light yellow
• Specific Gravity: 1.185
• Water Solubility: Reacts with water.
• Sensitive: Moisture Sensitive
• BRN: 507933
• InChI: 1S/C8H7ClO/c1-6-4-2-3-5-7(6)8(9)10/h2-5H,1H3
• InChIKey: GPZXFICWCMCQPF-UHFFFAOYSA-N
• SMILES: Cc1ccccc1C(Cl)=O
• CAS DataBase Reference: 933-88-0(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl chloride, 2-methyl-(933-88-0)
• EPA Substance Registry System: Benzoyl chloride, 2-methyl- (933-88-0)

Description and Uses

O-Toluoyl Chloride is used in the synthesis if quinolinone compounds as SARS CoV 3CLpro inhibitors. Also used in the synthesis of benzooxaboroles as orally active anti-inflammatory agents.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H314
• Precautionary statements: P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
• PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
• Hazard Codes: C
• Risk Statements: 34-36/37
• Safety Statements: 23-26-27-36/37/39-45-24/25
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• F: 10-19-21
• Hazard Note: Corrosive/Moisture Sensitive
• TSCA: TSCA listed
• HazardClass: 8
• PackingGroup: II
• HS Code: 29163900
• Storage Class: 8A - Combustible corrosive hazardous materials
• Hazard Classifications: Skin Corr. 1B
• Limited Quantities: 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)