A7706512
Trichlorphon solution , analyticalstandard,1.00mg/mlinmethanol , 52-68-6
Synonym(s):
(2,2,2-Trichloro-1-hydroxyethyl)phosphonic acid dimethyl ester;Metrifonate;Trichlorfon
CAS NO.：52-68-6
Empirical Formula: C4H8Cl3O4P
Molecular Weight: 257.44
MDL number: MFCD00055272
EINECS: 200-149-3
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 77-81 °C |
| Boiling point: | 100°C |
| Density | 1.73 |
| vapor pressure | 2.1×10-4Pa (20 °C) |
| refractive index | 1.3439 |
| storage temp. | 2-8°C |
| solubility | Freely soluble in water, very soluble in methylene chloride, freely soluble in acetone and in ethanol (96 per cent). |
| form | solid |
| pka | 6 (est.) |
| color | Crystals |
| Water Solubility | Slightly soluble. 1-5 g/100 mL at 21 ºC |
| Merck | 13,9696 |
| BRN | 1709434 |
| Stability: | Light Sensitive |
| IARC | 3 (Vol. 30, Sup 7) 1987 |
| NIST Chemistry Reference | Metrifonate(52-68-6) |
| EPA Substance Registry System | Trichlorfon (52-68-6) |
Description and Uses
Trichlorfon is a colorless crystalline powder. It is soluble in water (120 g/L) and most organic solvents, except aliphatic hydrocarbons. Log Kow = 0.43. Trichlorfon is rapidly converted to dichlorvos by alkalis (2) and then hydrolyzed; DT50 (22 ?C) values at pH 4, 7, and 9 are 510 d, 46 h, and <30 min, respectively.
Trichlorfon is an irreversible organophosophate acetylcholinesterase inhibitor and the prodrug of Dichlorvos (D435950). Trichlorfon have also shown potential actions to be utilized as an effective org anophosphorus pesticide.
Safety
| Symbol(GHS) |    GHS07,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H302+H312-H317-H334-H410 |
| Precautionary statements | P273-P280-P301+P312+P330-P302+P352+P312 |
| Hazard Codes | Xn,N |
| Risk Statements | 22-43-50/53 |
| Safety Statements | 24-37-60-61-2 |
| RIDADR | UN 3077 9/PG 3 |
| WGK Germany | 3 |
| RTECS | TA0700000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29319090 |
| Hazardous Substances Data | 52-68-6(Hazardous Substances Data) |
| Toxicity | LD50 in male, female rats (mg/kg): 630, 560 orally (Gaines) |
