Hydroxy-PEG5-CH2CO2tBu , 10mMinDMSO , 1807530-05-7

CAS NO.：1807530-05-7

Empirical Formula: C16H32O8

Molecular Weight: 352.42

MDL number: MFCD27977509

PRODUCT Properties

• Boiling point: 432.4±40.0 °C(Predicted)
• Density: 1.082±0.06 g/cm3(Predicted)
• storage temp.: Store at 0-8 °C
• solubility: Soluble in Water, DMSO, DCM, DMF
• pka: 14.36±0.10(Predicted)
• form: Liquid
• color: Colorless to light yellow

Description and Uses

Hydroxy-PEG5-CH2CO2tBu is a PEG linker containing a hydroxyl group with a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Hydroxy-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• HS Code: 2918999090