Home Categories Azido-PEG1-C1-Boc
M7441658

Azido-PEG1-C1-Boc , ≥95% , 1820717-35-8

CAS NO.:1820717-35-8

Empirical Formula: C8H15N3O3

Molecular Weight: 201.223

MDL number: MFCD27635154

Pack Size Price Stock Quantity
250mg RMB2594.40 In Stock
1g RMB6708.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

storage temp.  Store at Room Tem.
solubility  Soluble in DCM, DMF

Description and Uses

Azido-PEG1-CH2CO2-t-Bu is a azide (N3) containing PEG linker.The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Azido-PEG1-C1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1-C1-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501

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