![Indolo[2,1-b]quinazoline-6,12-dione](https://img.chemicalbook.com/CAS/GIF/13220-57-0.gif)
A7733058
Indolo[2,1-b]quinazoline-6,12-dione , 10mMinDMSO , 13220-57-0
Synonym(s):
Couroupitine A;Indolo(2,1-b)quinazoline-6,12-dione;Indolo[2,1-b]quinazoline-6,12-dione;NSC 349447;Tryptanthrine
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 258 °C(Solv: ethanol (64-17-5)) |
| Boiling point: | 469.3±28.0 °C(Predicted) |
| Density | 1.45±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble2mg/mL (warmed) |
| pka | -3.06±0.20(Predicted) |
| form | powder |
| color | faint yellow to dark yellow |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| Major Application | food and beverages |
| InChI | 1S/C15H8N2O2/c18-13-10-6-2-4-8-12(10)17-14(13)16-11-7-3-1-5-9(11)15(17)19/h1-8H |
| InChIKey | VQQVWGVXDIPORV-UHFFFAOYSA-N |
| SMILES | N21c3c(cccc3)C(=O)C2=Nc4c(cccc4)C1=O |
Description and Uses
The matured fruit of Couroupita guianensis yields two highly unsaturated alkaloids. Couroupitine A is obtained in the form of yellow needles when crystallized from MeOH-CHCI3. It gives an ultraivolet spectrum with absorption maxima at 225 and 251 nm and an inflexion at 315 nm in EtOH.
Tryptanthrin is natural alkaloid, and a potent inhibitor of cyclooxygenase COX-2 and 5-lipoxygenase acting as an anti-inflammatory agent.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P301+P312+P330 |
| WGK Germany | 3 |
| HS Code | 29339900 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral |
