PRODUCT Properties
| Melting point: | 214-215 °C(lit.) |
| Boiling point: | 333.35°C (rough estimate) |
| Density | 1.2319 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | room temp |
| solubility | Acetone (Slightly), Ethyl Acetate (Slightly) |
| form | Solid |
| pka | 6.32±0.40(Predicted) |
| color | Light Yellow to Yellow |
| Merck | 14,4339 |
| BRN | 272179 |
| InChI | InChI=1S/C15H10O5/c16-9-6-10(17)12-11(7-9)20-15(14(19)13(12)18)8-4-2-1-3-5-8/h1-7,16-17,19H |
| InChIKey | VCCRNZQBSJXYJD-UHFFFAOYSA-N |
| SMILES | C1(C2=CC=CC=C2)OC2=CC(O)=CC(O)=C2C(=O)C=1O |
| LogP | 3.322 (est) |
| CAS DataBase Reference | 548-83-4(CAS DataBase Reference) |
Description and Uses
Galangin is a flavonoid naturally found in herbs used in traditional medicine. Like many flavonoids, it has potent antioxidant properties. It also has anti-inflammatory actions related to suppression of signaling through NF-κB in mice. Galangin acts as an antagonist of the aryl hydrocarbon receptor, inducing apoptosis in cancer cells. It also inhibits cytochrome P450 isoform 1A1 with an IC50 value of less than 1 μM.
CYP1A1 inhibitor, vasodilator
