L-Leucine , 10mMinWater , 61-90-5
Synonym(s):
(S)-2-Amino-4-methylpentanoic acid;(S)-(+)-Leucine;Leu;L-Leucine;L-Leucine - CAS 61-90-5 - Calbiochem
CAS NO.：61-90-5
Empirical Formula: C6H13NO2
Molecular Weight: 131.17
MDL number: MFCD00002617
EINECS: 200-522-0
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | >300 °C (lit.) |
| Boiling point: | 122-134 °C(Press: 2-3 Torr) |
| alpha | 15.4 º (c=4, 6N HCl) |
| Density | 1,293 g/cm3 |
| bulk density | 300-400kg/m3 |
| vapor pressure | <1 hPa (20 °C) |
| refractive index | 1.4630 (estimate) |
| FEMA | 3297 | L-LEUCINE |
| Flash point: | 145-148°C |
| storage temp. | 2-8°C |
| solubility | 1 M HCl: 50 mg/mL |
| form | powder |
| pka | 2.328(at 25℃) |
| color | White to Off-white |
| PH | 5.5-6.5 (20g/l, H2O, 20℃) |
| Odor | at 100.00?%. odorless |
| biological source | plant |
| optical activity | [α]20/D +15.5°, c = 2 in 6 M HCl |
| Water Solubility | 22.4 g/L (20 C) |
| λmax | λ: 260 nm Amax: 0.05 λ: 280 nm Amax: 0.05 |
| Merck | 14,5451 |
| Sublimation | 145-148 ºC |
| JECFA Number | 1423 |
| BRN | 1721722 |
| Stability: | Stability Moisture and light sensitive. Incompatible with strong oxidising agents. |
| Major Application | peptide synthesis pharmaceutical (small molecule) |
| Cosmetics Ingredients Functions | SKIN CONDITIONING ANTISTATIC HAIR CONDITIONING |
| Cosmetic Ingredient Review (CIR) | L-Leucine (61-90-5) |
| InChI | 1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1 |
| InChIKey | ROHFNLRQFUQHCH-YFKPBYRVSA-N |
| SMILES | CC(C)C[C@H](N)C(O)=O |
| LogP | 0.80 |
| CAS DataBase Reference | 61-90-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Leucine(61-90-5) |
| EPA Substance Registry System | L-Leucine (61-90-5) |
Description and Uses
Small, white, lustrous plates, or a white, crystalline powder, with a slightly bitter taste. One g dissolves in about 40 mL of water and in about 100 mL of acetic acid. It is sparingly soluble in alcohol, but is soluble in dilute hydrochloric acid and in solutions of alkali hydroxides and carbonates. ι-Leucine may be synthesized by bromination, followed by amination of isocaproic acid; via the acetamidomalonic ester; by isolation from gluten, casein, keratin; from hydantoin.
L-Leucine is an essential amino acid. L-Leucine acts as a nutrient signal to stimulate protein synthesis. It has also activates the mammalian target of rapamycin kinase that regulates cell growth.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P271-P280 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| RTECS | OH2850000 |
| TSCA | TSCA listed |
| HS Code | 29224995 |
| Storage Class | 11 - Combustible Solids |
| Hazardous Substances Data | 61-90-5(Hazardous Substances Data) |
