Home Categories Biochemical Engineering TWS119
A7806612

TWS119 , ≥95% , 601514-19-6

Synonym(s):
3-[6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yloxy]phenol

CAS NO.:601514-19-6

Empirical Formula: C18H14N4O2

Molecular Weight: 318.33

MDL number: MFCD09037535

Pack Size Price Stock Quantity
10MG RMB559.20 In Stock
25MG RMB1355.20 In Stock
50MG RMB2430.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 249 °C
Density  1.42
storage temp.  2-8°C
solubility  insoluble in H2O; insoluble in EtOH; ≥15.9 mg/mL in DMSO
form  powder
pka 8.99±0.10(Predicted)
color  white to beige
InChI 1S/C18H14N4O2/c19-12-4-1-3-11(7-12)16-9-15-17(22-16)20-10-21-18(15)24-14-6-2-5-13(23)8-14/h1-10,23H,19H2,(H,20,21,22)
InChIKey VPVLEBIVXZSOMQ-UHFFFAOYSA-N
SMILES OC1=CC(OC2=NC=NC3=C2C=C(C4=CC=CC(N)=C4)N3)=CC=C1

Description and Uses

TWS119 has been used as glycogen synthase kinase-3β (GSK-3β) GSK3β inhibitor.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P305+P351+P338
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

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