Tofisopam , ≥98% , 22345-47-7

Synonym(s):
7,8-Dimethoxy-1-(3,4-dimethoxyphenyl)-5-ethyl-4-methyl-5H-2,3-benzodiazepine;EGYT 341;Seriel

CAS NO.：22345-47-7

Empirical Formula: C22H26N2O4

Molecular Weight: 382.45

MDL number: MFCD00823171

EINECS: 244-922-3

PRODUCT Properties

• Melting point: 155-159°C
• Boiling point: 509.61°C (rough estimate)
• Density: 1.2098 (rough estimate)
• refractive index: 1.6500 (estimate)
• solubility: DMSO: ~14 mg/mL
• pka: 7.29±0.40(Predicted)
• form: solid
• color: white
• λmax: 310nm(MeOH)(lit.)
• Merck: 14,9503
• Stability: Hygroscopic
• InChI: 1S/C22H26N2O4/c1-7-15-13(2)23-24-22(14-8-9-18(25-3)19(10-14)26-4)17-12-21(28-6)20(27-5)11-16(15)17/h8-12,15H,7H2,1-6H3
• InChIKey: RUJBDQSFYCKFAA-UHFFFAOYSA-N
• SMILES: CCC1C(C)=NN=C(c2ccc(OC)c(OC)c2)c3cc(OC)c(OC)cc13

Description and Uses

Tofisopam is a reagent used in preparation of allosteric ligands for pharmacological dark receptors GPR68 and GPR65. An anticonvulsant.

Safety

• Symbol(GHS): GHS07,GHS09
• Signal word: Warning
• Hazard statements: H302-H400
• Precautionary statements: P273-P301+P312+P330
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xn,N
• Risk Statements: 22-50
• Safety Statements: 60-61
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 2
• RTECS: DE9540000
• HS Code: 2933.99.8290
• HazardClass: 6.1(b)
• PackingGroup: III
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Acute Tox. 4 Oral; Aquatic Acute 1