3-(Trifluoromethyl)benzaldehyde , 95% , 454-89-7

Synonym(s):
α,α,α-Trifluoro-m-tolualdehyde

CAS NO.：454-89-7

Empirical Formula: C8H5F3O

Molecular Weight: 174.12

MDL number: MFCD00003373

EINECS: 207-228-1

PRODUCT Properties

• Boiling point: 83-86 °C30 mm Hg(lit.)
• Density: 1.301 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.465(lit.)
• Flash point: 155 °F
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: Liquid
• color: Clear colorless to very slightly orange
• Specific Gravity: 1.301
• Sensitive: Air Sensitive
• BRN: 2327537
• InChI: 1S/C8H5F3O/c9-8(10,11)7-3-1-2-6(4-7)5-12/h1-5H
• InChIKey: NMTUHPSKJJYGML-UHFFFAOYSA-N
• SMILES: [H]C(=O)c1cccc(c1)C(F)(F)F
• CAS DataBase Reference: 454-89-7(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 3-(trifluoromethyl)-(454-89-7)
• EPA Substance Registry System: Benzaldehyde, 3-(trifluoromethyl)- (454-89-7)

Description and Uses

3-(Trifluoromethyl)benzaldehyde is used as a reagent in the synthesis of 2,3-di- and 2,2,3-trisubstituted-3-methoxycarbonyl-╬│-butyrolactones as potent antitumor agents. Also used as a reagent in the synthesis of novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitors.

Safety

• Symbol(GHS): GHS07,GHS09
• Signal word: Warning
• Hazard statements: H315-H319-H335-H410
• Precautionary statements: P261-P264-P271-P273-P302+P352-P305+P351+P338
• target organs: Respiratory system
• PPE: Eyeshields, Gloves, type ABEK (EN14387) respirator filter
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: UN3082 - class 9 - PG 3 - DOT NA1993 - Environmentally hazardous substances, liquid, n.o.s. HI: all (not BR)
• WGK Germany: 3
• F: 10-23
• TSCA: TSCA listed
• HazardClass: IRRITANT
• HS Code: 29130000
• Storage Class: 10 - Combustible liquids
• Hazard Classifications: Aquatic Acute 1; Aquatic Chronic 2; Eye Irrit. 2; Skin Irrit. 2; STOT SE 3