Triisopropylsilyl Trifluoromethanesulfonate , 98% , 80522-42-5
Synonym(s):
TIPS triflate;Trifluoromethanesulfonic acid triisopropylsilyl ester;Triisopropylsilyl triflate
CAS NO.：80522-42-5
Empirical Formula: C10H21F3O3SSi
Molecular Weight: 306.42
MDL number: MFCD00009913
EINECS: 638-988-6
| Pack Size | Price | Stock | Quantity |
| 5G | RMB52.00 | In Stock |
|
| 10g | RMB79.20 | In Stock |
|
| 25G | RMB150.40 | In Stock |
|
| 100g | RMB568.80 | In Stock |
|
| 500g | RMB2648.80 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 45-46 °C/0.03 mmHg |
| Density | 1.14 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 213 °F |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Miscible with chloroform and ethyl acetate. |
| form | Liquid |
| Specific Gravity | 1.14 |
| color | Clear light brown to orange-brown |
| Sensitive | Moisture Sensitive |
| Hydrolytic Sensitivity | 8: reacts rapidly with moisture, water, protic solvents |
| BRN | 3591541 |
| InChI | InChI=1S/C10H21F3O3SSi/c1-7(2)18(8(3)4,9(5)6)16-17(14,15)10(11,12)13/h7-9H,1-6H3 |
| InChIKey | LHJCZOXMCGQVDQ-UHFFFAOYSA-N |
| SMILES | C(F)(F)(F)S(O[Si](C(C)C)(C(C)C)C(C)C)(=O)=O |
| CAS DataBase Reference | 80522-42-5(CAS DataBase Reference) |
Description and Uses
Triisopropylsilyl Trifluoromethanesulfonate is a highly reactive silylating agent and Lewis acid capable of converting primary and secondary alcohols to the corresponding triisopropylsilyl ethers and converting ketones and lactones into their enol silyl ethers; protection of terminal alkynes; promoting conjugate addition of alkynylzinc compounds to α,β-enones; preparation of (triisopropylsilyl)diazomethane, participating in the following (but not limited to) reactions: Silylation of Alcohols, Formations of Enol Silyl Ethers, Alkynyltriisopropylsilanes, Conjugate Addition of Alkynylzinc Bromides, (Triisopropylsilyl)diazomethane, Triisopropylsiloxycarbonyl (Tsoc) and BIPSOP Protecting Groups for Amines, TIPS Protection for Oxazoles/Regioselective Trapping of C-2 Oxazole Anions, Benzannulation Using Triisopropylsilyl Vinyl Ketenes, Cyclization of 1-Silyloxy-1,5-diynes, Desymmetrization of Tartaric Acid Esters etc.
Safety
| Symbol(GHS) |  GHS05 |
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 |
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter |
| Hazard Codes | C |
| Risk Statements | 34 |
| Safety Statements | 26-36/37/39-45-28A-27 |
| RIDADR | UN 3265 8/PG 2 |
| WGK Germany | 3 |
| F | 3-10-21 |
| TSCA | No |
| HazardClass | 8 |
| PackingGroup | II |
| HS Code | 29319090 |
| Storage Class | 8A - Combustible corrosive hazardous materials |
| Hazard Classifications | Skin Corr. 1B |
| Limited Quantities | 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) |
