Uridine 5′-diphosphoglucose disodium salt , 97.0%(HPLC) , 28053-08-9

Synonym(s):
UDPG hydrate;UDP-Glc hydrate

CAS NO.：28053-08-9

Empirical Formula: C15H25N2NaO17P2

Molecular Weight: 590.3

MDL number: MFCD00216890

EINECS: 248-801-6

PRODUCT Properties

• Melting point: >162°C (dec.)
• storage temp.: -20°C
• solubility: H2O: soluble50mg/mL, clear
• form: Solid
• color: White to Off-White
• biological source: Saccharomyces cerevisiae
• Water Solubility: H2O: 50mg/mL, clear
• BRN: 4290380
• Stability: Hygroscopic
• InChIKey: PKJQEQVCYGYYMM-XXXBXXKPSA-L
• SMILES: O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)O[C@H]1N1C=CC(=O)NC1=O)O.[NaH] |&1:1,2,3,14,15,16,18,20,26,r|

Description and Uses

Uridine 5'-diphosphoglucose disodium salt, secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose disodium salt is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose disodium salt is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue.

Disodium UDP-glucose is a phosphorylated uridine derivative used in nucleotide sugars metabolism as an activated form of glucose as a substrate for the enzyme glucosyltransferases. It is used in the treatment of chronic alcoholism. It is used in characterization of limonoid glucosyltransferase.

Safety

• PPE: Eyeshields, Gloves, type N95 (US)
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HS Code: 29400090
• Storage Class: 11 - Combustible Solids