D-Valine , 98% , 640-68-6

Synonym(s):
(R)-α-Aminoisovaleric acid;D-2-Amino-3-methylbutanoic acid

CAS NO.：640-68-6

Empirical Formula: C5H11NO2

Molecular Weight: 117.15

MDL number: MFCD00064219

EINECS: 211-368-9

PRODUCT Properties

• Melting point: >295 °C (subl.)(lit.)
• Boiling point: 213.6±23.0 °C(Predicted)
• alpha: -27.5 º (c=5, 5N HCl)
• Density: 1.2000 (estimate)
• refractive index: -27 ° (C=8, 6mol/L HCl)
• storage temp.: room temp
• solubility: 56 g/L (20°C)
• form: Crystalline Powder
• pka: 2.37±0.10(Predicted)
• color: White to off-white
• biological source: synthetic (organic)
• optical activity: [α]23/D 32.0 to 24.0°, c = 8 in 6 M HCl
• Water Solubility: 56 g/L (20 ºC)
• BRN: 1721135
• InChIKey: KZSNJWFQEVHDMF-SCSAIBSYSA-N
• LogP: 0.289 (est)
• CAS DataBase Reference: 640-68-6(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-3-methylbutanoic acid(D)(640-68-6)
• EPA Substance Registry System: D-Valine (640-68-6)

Description and Uses

D-Valine is an isomer of the essential amino acid L-Valine. D-Valine has been used as a selective agent in epithelial cells in culture since it inhibits cells that lack the enzyme D-amino acid oxidase. D-Valine has also been shown to inhibit proliferation of contaminating fibroblasts in smooth muscle cells from human myometrium. D-Valine solution showed tumor growth inhibition and improvements of the nutritional status in AH109A hepatoma-bearing rats.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P271-P280
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• RTECS: YV9360000
• TSCA: Yes
• HS Code: 29224995