Vincamine , 98% , 1617-90-9

CAS NO.：1617-90-9

Empirical Formula: C21H26N2O3

Molecular Weight: 354.44

MDL number: MFCD00078054

EINECS: 216-576-3

PRODUCT Properties

• Melting point: 232 °C (dec.)(lit.)
• Boiling point: 487.66°C (rough estimate)
• alpha: 42.8 º (c=1 in pyridine)
• Density: 1.1640 (rough estimate)
• refractive index: 1.6500 (estimate)
• storage temp.: Keep in dark place,Inert atmosphere,2-8°C
• solubility: Chloroform (Slightly), DMSO (Slightly)
• form: Solid
• pka: 12.13±0.40(Predicted)
• color: White to Off-White
• optical activity: [α]23/D +42.8°, c = 1 in pyridine
• Merck: 14,9983
• Stability: Hygroscopic
• Major Application: food and beverages
• InChI: 1S/C21H26N2O3/c1-3-20-10-6-11-22-12-9-15-14-7-4-5-8-16(14)23(17(15)18(20)22)21(25,13-20)19(24)26-2/h4-5,7-8,18,25H,3,6,9-13H2,1-2H3/t18-,20+,21+/m1/s1
• InChIKey: RXPRRQLKFXBCSJ-GIVPXCGWSA-N
• SMILES: CC[C@@]12CCCN3CCc4c(C13)n(c5ccccc45)[C@](O)(C2)C(=O)OC
• LogP: 3.100 (est)
• NIST Chemistry Reference: Vincamine(1617-90-9)

Description and Uses

Vincamine is an alkaloid extracted from the leaves of the Vinca minor and is a related synthetic ethyl ester of vincaminic acid. It has spasmolytic effects similar to reserpine and can potentially improve blood flow in the brain.

Vincamine is often used as a nootropic agent to combat the effects of aging, or in conjunction with other nootropics (such as piracetam) for a variety of purposes. Vincamine is a peripheral vasodilator that increases blood flow to the brain.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P264-P270-P301+P312-P501
• Hazard Codes: Xn
• Risk Statements: 22
• Safety Statements: 36-26
• WGK Germany: 3
• RTECS: YY8575000
• HS Code: 29399990
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Acute Tox. 4 Oral
• Hazardous Substances Data: 1617-90-9(Hazardous Substances Data)
• Toxicity: LD50 in mice (mg/kg): 75 i.v.; >1000 s.c. (Szporny, Szász); 1000 orally (Szabo, Nagy)