Vecuronium Bromide , ≥99% , 50700-72-6

Synonym(s):
1-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-piperidinium bromide;Vecuronium bromide

CAS NO.：50700-72-6

Empirical Formula: C34H57BrN2O4

Molecular Weight: 637.731

MDL number: MFCD00867762

EINECS: 256-723-9

PRODUCT Properties

• Melting point: 227-229°C
• alpha: +30.5～+35.0゜(D/20℃)(c=0.5,dil.HCl)
• storage temp.: Inert atmosphere,Store in freezer, under -20°C
• solubility: Slightly soluble in water, freely soluble in methylene chloride, sparingly soluble in acetonitrile and in anhydrous ethanol.
• form: Solid
• color: White
• biological source: synthetic
• Merck: 14,9941
• BRN: 4837308
• Stability: Hygroscopic
• InChIKey: VEPSYABRBFXYIB-PWXDFCLTSA-M
• SMILES: [Br-].CC(=O)O[C@H]1C[C@@H]2CC[C@@H]3[C@H](CC[C@@]4(C)[C@H]3C[C@@H]([C@@H]4OC(C)=O)[N+]5(C)CCCCC5)[C@@]2(C)C[C@@H]1N6CCCCC6
• CAS DataBase Reference: 50700-72-6(CAS DataBase Reference)

Description and Uses

Vecuronium is a non-depolarizing muscle relaxant derived from the aminosteroid pancuronium and used adjunctively to general anesthesia. It competitively blocks cholinergic receptors at the motor end plate of the neuromuscular junction, inducing temporary paralysis. In humans, it has been shown to reduce muscle twitch tension with an ED₅₀ value of 0.15 mg/kg for a duration of 27 minutes without inducing cardiovascular effects.

An aminosteroid, competitive neuromuscular blocker agent.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P301+P312+P330
• PPE: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• Hazard Codes: Xi,Xn
• Risk Statements: 36/37/38-22
• Safety Statements: 26-37/39
• WGK Germany: 3
• RTECS: TN4875000
• HS Code: 2933399090
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Acute Tox. 4 Oral
• Toxicity: LD50 in mice: 0.061 mg/kg i.v. (Buckett)