4-Methyl-2-thiazolecarboxaldehyde , 97% , 13750-68-0

CAS NO.：13750-68-0

Empirical Formula: C5H5NOS

Molecular Weight: 127.16

MDL number: MFCD00022450

EINECS: 627-825-4

PRODUCT Properties

• Boiling point: 72-74 °C9 mm Hg(lit.)
• Density: 1.183 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.5600(lit.)
• Flash point: 153 °F
• storage temp.: -20°C, sealed storage, away from moisture
• pka: 0.86±0.10(Predicted)
• form: liquid
• color: Pale yellow
• InChI: 1S/C5H5NOS/c1-4-3-8-5(2-7)6-4/h2-3H,1H3
• InChIKey: NYMCQLLAIMUVSY-UHFFFAOYSA-N
• SMILES: [H]C(=O)c1nc(C)cs1
• LogP: 0.963 (est)

Description and Uses

4-Methyl-1,3-thiazole-2-carbaldehyde is used to prepare selective cyclooxygenase-2 inhibitors. Thiazole containing compounds demonstrated excellent oral activity.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H317-H319
• Precautionary statements: P261-P264-P280-P301+P312-P302+P352-P305+P351+P338
• PPE: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
• Hazard Codes: Xn
• Risk Statements: 22-36-43
• Safety Statements: 26-36/37
• RIDADR: NA 1993 / PGIII
• WGK Germany: 3
• HS Code: 29341000
• Storage Class: 10 - Combustible liquids
• Hazard Classifications: Acute Tox. 4 Oral; Eye Irrit. 2; Skin Sens. 1