PRODUCT Properties
| Melting point: | 124-127 °C (lit.) |
| Boiling point: | 241.3±40.0℃ (760 Torr) |
| Density | 1.335±0.06 g/cm3 (20 ºC 760 Torr) |
| Flash point: | 99.7±27.3℃ |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 15.31±0.50(Predicted) |
| Appearance | White to off-white Solid |
| BRN | 1955599 |
| InChI | 1S/C8H6F3NO/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H2,12,13) |
| InChIKey | XBGXGCOLWCMVOI-UHFFFAOYSA-N |
| SMILES | NC(=O)c1cccc(c1)C(F)(F)F |
| CAS DataBase Reference | 1801-10-1(CAS DataBase Reference) |
Description and Uses
3-(Trifluoromethyl)benzamide can be prepared from 1-bromo-3-trifluoromethylbenzene via palladium-catalyzed aminocarbonylation with formamide. It forms the core moiety of N-[(substituted 1H-imidazol-1-yl)propyl]benzamides, with potential as antihypertensive agents.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 2924297099 |
| Storage Class | 11 - Combustible Solids |
