1-Methyl-3-indoleacetic acid , 98% , 1912-48-7

Synonym(s):
2-(N-Methylindole-3-yl)acetic acid;NSC 78007

CAS NO.：1912-48-7

Empirical Formula: C11H11NO2

Molecular Weight: 189.21

MDL number: MFCD00130160

PRODUCT Properties

• Melting point: 126-128 °C (lit.)
• Boiling point: 392.0±17.0 °C(Predicted)
• Density: 1.20±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: Chloroform, Methanol
• pka: 4.53±0.30(Predicted)
• form: Crystalline Powder
• color: White to tan
• InChI: InChI=1S/C11H11NO2/c1-12-7-8(6-11(13)14)9-4-2-3-5-10(9)12/h2-5,7H,6H2,1H3,(H,13,14)
• InChIKey: NAIPEFIYIQFVFC-UHFFFAOYSA-N
• SMILES: N1(C)C2=C(C=CC=C2)C(CC(O)=O)=C1

Description and Uses

• Reactant for enantioselective preparation of α-aryl alkylcarboxylic acids
• Reactant for preparation of PKC inhibitor methylindolylpyridinylmethylpiperidinylindolylpyrroledione for protein kinase C imaging
• Reactant for stereoselective preparation of δ-lactones via Michael addition/lactonization with unsaturated carboxylates
• Reactant for stereoselective preparation of vindorosine, vindoline, and analogs
• Reactant for preparation of (indolyl)pyrrol-2-ones as VEGF-R inhibitors, antiangiogenic agents, and protein kinase inhibitors
• Reactant for synthesis of 3-aryl-5-alkyl-2,5-dihydrofuran-2-ones and their carbanalogues as antifungal agents

Safety

• Symbol(GHS): GHS05,GHS07
• Signal word: Danger
• Hazard statements: H302-H315-H318-H335
• Precautionary statements: P261-P280-P305+P351+P338
• target organs: Respiratory system
• Hazard Codes: Xn
• Risk Statements: 22-37/38-41
• Safety Statements: 26-39
• WGK Germany: 3
• HazardClass: IRRITANT
• HS Code: 2933998090
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Acute Tox. 4 Oral; Eye Dam. 1; Skin Irrit. 2; STOT SE 3