Propargyl-Peg8-t-Butylester , 95% , 2055014-96-3
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB388.80 | In Stock |
|
| 250mg | RMB660.80 | In Stock |
|
| 1g | RMB1783.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 528.4±45.0 °C(Predicted) |
| Density | 1.064±0.06 g/cm3(Predicted) |
| storage temp. | Storage temp. 2-8°C |
| solubility | Soluble in Water, DMSO, DCM, DMF |
| form | Liquid |
| color | Colorless to light yellow |
Description and Uses
Propargyl-PEG8-t-butyl ester is a PEG reagent with an alkyne group and a t-butyl group. The alkyne group enables the formation of triazole linkage with azide-bearing compounds or biomolecules; copper is required as a catalyst. The t-butyl group can be hydrolyzed under acidic conditions. The hydrophicility of the molecule is improved by having 8 units of PEG.
Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG8-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H401 |
| Precautionary statements | P501-P273-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
