9-((1R,4S)-4-(tert-Butoxymethyl)cyclopent-2-en-1-yl)-N6-cyclopropyl-9H-purine-2,6-diamine , 98% , 1443421-68-8

CAS NO.：1443421-68-8

Empirical Formula: C18H26N6O

Molecular Weight: 342.44

MDL number:

PRODUCT Properties

• Boiling point: 580.3±60.0 °C(Predicted)
• Density: 1.40±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: Solid
• pka: 4.86±0.10(Predicted)
• color: Pale Orange to Light Orange
• Major Application: pharmaceutical
• InChI: 1S/C18H26N6O/c1-18(2,3)25-9-11-4-7-13(8-11)24-10-20-14-15(21-12-5-6-12)22-17(19)23-16(14)24/h4,7,10-13H,5-6,8-9H2,1-3H3,(H3,19,21,22,23)/t11-,13+/m1/s1
• InChIKey: GUTJAVLKEBLQJK-YPMHNXCESA-N
• SMILES: [n]2(c3nc(nc(c3nc2)NC4CC4)N)[C@@H]1C[C@@H](C=C1)COC(C)(C)C

Description and Uses

N6-Cyclopropyl-9-[(1R,4S)-4-[(1,1-dimethylethoxy)methyl]-2-cyclopenten-1-yl]-9H-purine-2,6-diamine (Abacavir EP Impurity F) is an impurity of Abacavir (A104990), a guanosine analog that inhibits reverse transcriptase (NRTI)?(1,2).

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• WGK Germany: WGK 3
• Storage Class: 11 - Combustible Solids