N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine , 95% , 477600-73-0

CAS NO.：477600-73-0

Empirical Formula: C20H25N5

Molecular Weight: 335.45

MDL number: MFCD16877475

Pack Size	Price	Stock	Quantity
100mg	RMB114.40	In Stock
250mg	RMB200.00	In Stock
1g	RMB501.60	In Stock
5g	RMB1756.00	In Stock
25g	RMB5971.20	In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point:	67-69℃
Density	1.205±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	13.36±0.50(Predicted)
InChI	InChI=1S/C20H25N5/c1-15-9-11-25(12-16-6-4-3-5-7-16)13-18(15)24(2)20-17-8-10-21-19(17)22-14-23-20/h3-8,10,14-15,18H,9,11-13H2,1-2H3,(H,21,22,23)/t15-,18+/m1/s1
InChIKey	UMWNXPTXDOVDFE-QAPCUYQASA-N
SMILES	C1=NC(N(C)[C@@H]2[C@H](C)CCN(CC3=CC=CC=C3)C2)=C2C=CNC2=N1

Description and Uses

N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine is an important pharmaceutical intermediate used for the synthesis of tofacitinib. Tofacitinib is a Janus kinase (JAK) inhibitor drug used to treat rheumatoid arthritis and psoriatic arthritis.

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