BD0460245
tert-Butyl(2-(2-bromoethoxy)ethyl)carbamate , 95% , 164332-88-1
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB79.20 | In Stock |
|
| 250mg | RMB132.00 | In Stock |
|
| 1g | RMB353.60 | In Stock |
|
| 5g | RMB1257.60 | In Stock |
|
| 25g | RMB4625.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 336.6±22.0 °C(Predicted) |
| Density | 1.283±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Soluble in Water, DMSO, DCM, DMF |
| pka | 12.19±0.46(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
| InChI | InChI=1S/C9H18BrNO3/c1-9(2,3)14-8(12)11-5-7-13-6-4-10/h4-7H2,1-3H3,(H,11,12) |
| InChIKey | DMOPZPBTLCZSGL-UHFFFAOYSA-N |
| SMILES | C(OC(C)(C)C)(=O)NCCOCCBr |
Description and Uses
Tert-Butyl (2-(2-bromoethoxy)ethyl)carbamate (t-boc-N-amido-PEG2-bromide) is a PEG derivative containing a bromide group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.
tert-Butyl (2-(2-bromoethoxy)ethyl)carbamate is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
